The Möbius Inversion is a small wormhole characterized by level-6 subspace distortions and gravimetric shear. It is located in the Delta Quadrant, where it covers the last third of the course for the Antarian Trans-stellar Rally. In the 2377 running of the Rally, high levels of radiation from the Möbius Inversion blocked the sensors of the Delta Flyer. When it entered the Möbius Inversion, its status from outside the wormhole was unknown. While in the Möbius Inversion, the Delta Flyer reversed their deflector polarity to deflect the shields of two rival vessels, creating a gap for it to pass through and take the lead. (VOY: "Drive")

There have been various wormhole models developed in real physics but none of them are named "Möbius Inversions". Lorentzian wormholes are mainly studied in general relativity and semiclassical gravity, while Euclidean wormholes are studied in particle physics. Traversable wormholes are a special kind of Lorentzian wormholes which would allow a human to travel from one side of the wormhole to the other. Lorentzian wormholes known as Schwarzschild wormholes or Einstein-Rosen bridges are bridges between areas of space that can be modeled as vacuum solutions to the Einstein field equations by combining models of a black hole and a white hole.

The name Möbius Inversion may have been conceived by the writers of Star Trek as a homage to mathematician August Möbius - a German mathematician and theoretical astronomer who is best known for his discovery of the Möbius strip, a non-orientable two-dimensional surface with only one side when embedded in three-dimensional Euclidean space.