In Star Trek, the Amargosa Diaspora is an enormous globular cluster of unusually high density. One of its formations is FGC 13, a stellar cluster. In 2369, the USS Enterprise-D was assigned to chart this region. To expedite the process, Lieutenant Commander Geordi La Forge devised a way to enhance the long-range sensors by transferring warp power to the main deflector grid. His modifications attracted the attention of solanagen-based lifeforms to the ship. (TNG: "Schisms"). Amargosa was the primary star of the Amargosa system, studied by a Federation observatory where Dr. Tolian Soran developed his trilithium weapon. From the observatory, Soran launched the weapon into Amargosa in 2371 and collapsed the star, producing a level-12 shock wave that destroyed everything in the system. The collapse of Amargosa had several repercussions in its sector of space. These effects included an increase in gamma emissions of .05%, gravitational forces were altered, forcing the USS Bozeman to make a minor course correction. The same forces altered the flight path of the Nexus ribbon as Soran had planned, as part of his attempt to bring the ribbon to a planet. (Star Trek Generations). It is unknown if the collapse of the Amargosa star developed a quantum singularity, a dwarf star, or completely destroyed it.

The word diaspora refers to the the spatial property of being scattered about over a range or area. There is no such globular cluster as the Amargosa Diaspora in real astronomy. However, the jumbled rocks of the Virgin Spring area in the Black Mountains is complexly faulted and folded, and this part of Death Valley has been named by geologists as the ‘Amargosa chaos'. These multi-colored and oddly-shaped mountains look as if Mother Nature had scattered and thrown them together in a most twisted and random manner.

The FGC referred to in FGC 13 stands for Federation General Catalogue. The real-science equivalent is NGC (New General Catalogue) - a well-known catalogue of deep sky objects in amateur astronomy. NGC 13 in this catalogue is a spiral galaxy in the Andromeda constellation.